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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name hsa-miR-4513
ncRNA Category miRNA
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line RPE cells (ARPE), brain samples
Methods qPCR, TaqMan miRNA assay, luciferase reporter assay, Western blot
Expression pattern associated
Functional description We identified three variants in miRNAs significantly associated with AMD.rs2168518, is located at the seed sequence of miR-4513.miR-4513 plays a pleiotropic role in cardiovascular disease and AMD.
PubMed ID 28397307
Year 2017
Title Genetic variants in microRNAs and their binding sites within gene 3'UTRs associate with susceptibility to age-related macular degeneration.
Drug-related ncRNA NO

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