ncRNA name | hsa-miR-4513 |
ncRNA Category | miRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Homo sapiens |
Tissues/Cell_line | RPE cells (ARPE), brain samples |
Methods | qPCR, TaqMan miRNA assay, luciferase reporter assay, Western blot |
Expression pattern | associated |
Functional description | We identified three variants in miRNAs significantly associated with AMD.rs2168518, is located at the seed sequence of miR-4513.miR-4513 plays a pleiotropic role in cardiovascular disease and AMD. |
PubMed ID | 28397307 |
Year | 2017 |
Title | Genetic variants in microRNAs and their binding sites within gene 3'UTRs associate with susceptibility to age-related macular degeneration. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.